Endocrine Abstracts

Introduction: Primary aldosteronism (PA) is associated with increased prevalence of metabolic disorders such as impaired glucose and lipid metabolism and insulin resistance. Individuals with PA have an increased risk of cardiovascular events. The aim of this study is to determine the characteristics of metabolic syndrome (MS) in patients with PA.Patients and methods: Retrospective study concerning 40 patients with PA over the period of 10 years from Janu...

Introduction: Primary hyperaldosteronism (PA) is the autonomous production of aldosterone by a disease primarily affecting the glomerular zone of the adrenal gland. It is one of the most frequent causes of secondary hypertension. The diagnosis should be suspected in the presence of the classic clinico-biological triad in patients presenting with hypertension, low plasma renin activity (PRA), with or without hypokalemia.Patients and Methods: Retrospective...

Introduction: Primary aldosteronism (PA) is commonly identified as the main cause of secondary hypertension. It is becoming increasingly wide-spread, affecting between 1 and 30% of people suffering from hypertension. We aim to describe the epidemiological, clinical and paraclinical characteristics of PA and to analyse its therapeutic and evolutionary aspects.Patients and methods: Retrospective and descriptive study concerning 40 patients with PA, collect...

Introduction: Primary aldosteronism (PA) is commonly identified as the main cause of secondary hypertension. It is becoming increasingly wide-spread, affecting between 1 and 30% of people suffering from hypertension. We aim to determine the different characteristics between aldosterone-producing adenoma (APA) and bilateral adrenal hyperplasia (BAH).Patients and methods: Retrospective descriptive and analytical study concerning 40 patients with PA, collec...

Introduction: Primary aldosteronism (PA) is commonly identified as the main cause of secondary hypertension. It is becoming increasingly wide-spread, affecting between 1 and 30% of people suffering from hypertension. A prolonged exposure to high aldosterone concentrations has a deleterious effect on cardiovascular tissues and is associated with target organ damage, independently of blood pressure, so a higher risk of cardiovascular events has been reported in patients with pri...

Introduction: Primary aldosteronism (PA) is frequently recognized as the main cause of secondary hypertension. Its prevalence is on the rise, impacting a range of 1 to 30% among individuals with hypertension.Patients and methods: Retrospective and descriptive study concerning 40 patients with PA, collected in the endocrinology department of the Hedi Chaker University Hospital of Sfax, over the period of 10 years from January 2010 to December 2022.<p ...

Introduction: Myasthenia gravis (MG) is a chronic neuromuscular condition characterized by weakness in voluntary muscles. It is an autoimmune disorder. The emergence of the condition can be abrupt. As with any autoimmune disease (AID), it may be associated with other AIDs. We report a case of MG associated with Hashimoto’s thyroiditis (HT).Observation: The diagnosis of MG was established in a 58-year-old patient, based on the progressive onset of fa...

Introduction: Despite being organ-specific autoimmune diseases (AID), autoimmune thyroid diseases (AITD) may be associated with other AIDs either specific to other organs or systemic. These associations are not uncommon. They may be grouped in the form of an autoimmune polyendocrinopathy or multiple autoimmune syndrome (MAS). MAS is defined by the presence in the same person of at least three AIDs.Patients and Methods: It is a retrospective study over a ...

Introduction: Overt hyperthyroidism is the result of excessive production of thyroid hormones. The diagnosis is made on the basis of clinical characteristics and the diagnosis of certainty is made by hormone assay, combining low TSH with increased thyroid hormones. If the hyperthyroidism is left untreated, symptoms progress and can lead to complications that may jeopardize life prognosis.Patients and Methods: A retrospective study involving 29 patients w...

Introduction: Graves’ disease (GD), an autoimmune disorder predominantly impacting the thyroid gland, can extend its effects to various organs, such as the eyes and skin. It stands as the leading cause of hyperthyroidism. It is defined by the pathognomonic combination of thyrotoxicosis, goitre and exophthalmos. The aim of this study was to identify the characteristics of GD.Patients and Methods: A retrospective study involving 31 patients with prima...